Recent FPbase Activity

Most Viewed Proteins

As a percentage of total protein page views.
  1. EGFP 6.5%
  2. mCherry 6.0%
  3. mScarlet 3.7%
  4. mNeonGreen 2.8%
  5. avGFP 2.5%
  6. Superfolder GFP 2.5%
  7. mScarlet3 2.0%
  8. tdTomato 1.9%
  9. DsRed 1.8%
  10. mStayGold 1.5%
  11. StayGold 1.4%
  12. Venus 1.4%

Most Favorited Proteins

  1. mCherry 216
  2. EGFP 170
  3. mNeonGreen 151
  4. mScarlet 110
  5. tdTomato 103
  6. mTagBFP2 96
  7. mTurquoise2 86
  8. mScarlet-I 79
  9. Superfolder GFP 78
  10. mKate2 54
  11. mVenus 53
  12. EYFP 48
  13. TagBFP 45
  14. mScarlet3 45
  15. mRuby3 37
  16. mEGFP 37
  17. mTFP1 36
  18. DsRed 36

Recently Published

smURFP_2.5

published: Nov 26, 2025

Kulhanek et al. (2025) Engineering a Bright Near-Infrared Fluorescent Protein by Screening a Comprehensive Phenotypic Landscape. . doi:10.1101/2025.11.25.690577. Article

pHluorin4

published: Oct 18, 2025

Thornell (2025) The <scp>pH</scp> ‐dependent photophysical and spectral properties of <scp>pH</scp> ‐sensing green fluorescent proteins. Physiological Reports. doi:10.14814/phy2.70625. Article   Pubmed

Var1

published: Oct 2, 2025

Gao et al. (2025) Autonomous liquid-handling robotics scripting through large language models enables accessible and safe protein engineering workflows. . doi:10.1101/2025.09.30.679666. Article

Diogenes

published: Jul 25, 2025

Ruchkin et al. (2025) Two Key Substitutions in the Chromophore Environment of mKate2 Produce an Enhanced FusionRed-like Red Fluorescent Protein. Acta Naturae. doi:10.32607/actanaturae.27545. Article   Pubmed

mEos4Fast2

published: Jul 16, 2025

Maity et al. (2025) Decoding mEos4b day‐long maturation and engineering fast‐maturing variants. Protein Science. doi:10.1002/pro.70234. Article   Pubmed

mEos4b-L93M

published: Jul 16, 2025

Maity et al. (2025) Decoding mEos4b day‐long maturation and engineering fast‐maturing variants. Protein Science. doi:10.1002/pro.70234. Article   Pubmed

mEos4Fast1

published: Jul 16, 2025

Maity et al. (2025) Decoding mEos4b day‐long maturation and engineering fast‐maturing variants. Protein Science. doi:10.1002/pro.70234. Article   Pubmed

YuzuFP spectrum

YuzuFP

published: Jun 5, 2025

Ahmed et al. (2025) Molecular dynamics guided identification of a brighter variant of superfolder Green Fluorescent Protein with increased photobleaching resistance. Communications Chemistry. doi:10.1038/s42004-025-01573-4. Article   Pubmed

mScarlet3-H spectrum

mScarlet3-H

published: Apr 17, 2025

Xiong et al. (2025) A highly stable monomeric red fluorescent protein for advanced microscopy. Nature Methods. doi:10.1038/s41592-025-02676-5. Article   Pubmed

mGold2s spectrum

mGold2s

published: Apr 4, 2025

Lee et al. (2025) Bright and photostable yellow fluorescent proteins for extended imaging. Nature Communications. doi:10.1038/s41467-025-58223-5. Article   Pubmed

mGold2t spectrum

mGold2t

published: Apr 4, 2025

Lee et al. (2025) Bright and photostable yellow fluorescent proteins for extended imaging. Nature Communications. doi:10.1038/s41467-025-58223-5. Article   Pubmed

nirFAST + HPAR-3,5DOM spectrum

nirFAST + HPAR-3,5DOM

published: Mar 16, 2025

El Hajji et al. (2025) A tunable and versatile chemogenetic near-infrared fluorescent reporter. Nature Communications. doi:10.1038/s41467-025-58017-9. Article   Pubmed

mTurquoise2_T203Y spectrum

mTurquoise2_T203Y

published: Jan 2, 2025

van der Linden et al. (2025) A green lifetime biosensor for calcium that remains bright over its full dynamic range. . doi:10.7554/elife.105086. Article

mScarlet3-S2 spectrum

mScarlet3-S2

published: Dec 24, 2024

Xu et al. (2024) A highly photostable monomeric red fluorescent protein. . doi:10.21203/rs.3.rs-5629743/v1. Article

StayRose spectrum

StayRose

published: Dec 17, 2024

Scott et al. (2024) StayRose: a photostable StayGold derivative red-shifted by genetic code expansion. . doi:10.1101/2024.12.13.628370. Article

Recently Added to FPbase

afCFP

added: Dec 3, 2025

Katayama et al. (2020) Visualizing and Modulating Mitophagy for Therapeutic Studies of Neurodegeneration. Cell. doi:10.1016/j.cell.2020.04.025. Article   Pubmed

smURFP_2.5

added: Nov 26, 2025

Kulhanek et al. (2025) Engineering a Bright Near-Infrared Fluorescent Protein by Screening a Comprehensive Phenotypic Landscape. . doi:10.1101/2025.11.25.690577. Article

mTagBFP

added: Nov 25, 2025

Subach et al. (2011) An Enhanced Monomeric Blue Fluorescent Protein with the High Chemical Stability of the Chromophore. PLoS ONE. doi:10.1371/journal.pone.0028674. Article   Pubmed

pHluorin4

added: Nov 24, 2025

Thornell (2025) The <scp>pH</scp> ‐dependent photophysical and spectral properties of <scp>pH</scp> ‐sensing green fluorescent proteins. Physiological Reports. doi:10.14814/phy2.70625. Article   Pubmed

Var1

added: Nov 24, 2025

Gao et al. (2025) Autonomous liquid-handling robotics scripting through large language models enables accessible and safe protein engineering workflows. . doi:10.1101/2025.09.30.679666. Article

mTurquoise2_T203Y spectrum

mTurquoise2_T203Y

added: Nov 1, 2025

van der Linden et al. (2025) A green lifetime biosensor for calcium that remains bright over its full dynamic range. . doi:10.7554/elife.105086. Article

pFAST + HBIR-3M

added: Oct 1, 2025

Benaissa et al. (2021) Engineering of a fluorescent chemogenetic reporter with tunable color for advanced live-cell imaging. Nature Communications. doi:10.1038/s41467-021-27334-0. Article   Pubmed

nirFAST + HPAR-3,5DOM spectrum

nirFAST + HPAR-3,5DOM

added: Oct 1, 2025

El Hajji et al. (2025) A tunable and versatile chemogenetic near-infrared fluorescent reporter. Nature Communications. doi:10.1038/s41467-025-58017-9. Article   Pubmed

Crimson

added: Sep 22, 2025

Ning et al. (2022) A Bright, Nontoxic, and Non-aggregating red Fluorescent Protein for Long-Term Labeling of Fine Structures in Neurons. Frontiers in Cell and Developmental Biology. doi:10.3389/fcell.2022.893468. Article   Pubmed

mEos4Fast2

added: Sep 19, 2025

Maity et al. (2025) Decoding mEos4b day‐long maturation and engineering fast‐maturing variants. Protein Science. doi:10.1002/pro.70234. Article   Pubmed

mEos4Fast1

added: Sep 19, 2025

Maity et al. (2025) Decoding mEos4b day‐long maturation and engineering fast‐maturing variants. Protein Science. doi:10.1002/pro.70234. Article   Pubmed

mEos4b-L93M

added: Sep 19, 2025

Maity et al. (2025) Decoding mEos4b day‐long maturation and engineering fast‐maturing variants. Protein Science. doi:10.1002/pro.70234. Article   Pubmed

RLuc8 spectrum

RLuc8

added: Sep 10, 2025

Loening (2006) Consensus guided mutagenesis of Renilla luciferase yields enhanced stability and light output. Protein Engineering Design and Selection. doi:10.1093/protein/gzl023. Article   Pubmed

Diogenes

added: Aug 26, 2025

Ruchkin et al. (2025) Two Key Substitutions in the Chromophore Environment of mKate2 Produce an Enhanced FusionRed-like Red Fluorescent Protein. Acta Naturae. doi:10.32607/actanaturae.27545. Article   Pubmed

YuzuFP spectrum

YuzuFP

added: Jun 16, 2025

Ahmed et al. (2025) Molecular dynamics guided identification of a brighter variant of superfolder Green Fluorescent Protein with increased photobleaching resistance. Communications Chemistry. doi:10.1038/s42004-025-01573-4. Article   Pubmed

eUnaG

added: May 25, 2025

Yeh et al. (2017) eUnaG: a new ligand-inducible fluorescent reporter to detect drug transporter activity in live cells. Scientific Reports. doi:10.1038/srep41619. Article   Pubmed

WiPhy2

added: May 12, 2025

Lehtivuori et al. (2015) Removal of Chromophore-Proximal Polar Atoms Decreases Water Content and Increases Fluorescence in a Near Infrared Phytofluor. Frontiers in Molecular Biosciences. doi:10.3389/fmolb.2015.00065. Article   Pubmed

StayRose spectrum

StayRose

added: May 12, 2025

Scott et al. (2024) StayRose: a photostable StayGold derivative red-shifted by genetic code expansion. . doi:10.1101/2024.12.13.628370. Article