Red fluorescent cAMP indicator with increased affinity and expanded dynamic range

Ohta Y, Furuta T, Nagai T, Horikawa K

(2018). Scientific Reports, 8(1) , 1866. doi: 10.1038/s41598-018-20251-1. Article   Pubmed

    Primary Proteins:
  1. R-FlincA
Add photostability measurements


"Seeking an indicator with improved detection sensitivity, we performed insertion screening of circularly permuted mApple, a red fluorescent protein, into the cAMP-binding motif of PKA regulatory subunit Iα and developed an improved cAMP indicator named R-FlincA (Red Fluorescent indicator for cAMP)."