Comparison List


R-FlincA is a basic (constitutively fluorescent) red fluorescent protein published in 2018.

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Oligomerization Organism Molecular Weight Cofactor
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FPbase ID: DP2EW


Ex λ Em λ EC (M-1 cm-1) QY Brightness pKa Maturation (min) Lifetime (ns)
560 585          


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R-FlincA Sequence

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"Seeking an indicator with improved detection sensitivity, we performed insertion screening of circularly permuted mApple, a red fluorescent protein, into the cAMP-binding motif of PKA regulatory subunit Iα and developed an improved cAMP indicator named R-FlincA (Red Fluorescent indicator for cAMP)."

Ohta et al. (2018)

Primary Reference

Red fluorescent cAMP indicator with increased affinity and expanded dynamic range

Ohta Y, Furuta T, Nagai T, Horikawa K

(2018). Scientific Reports, 8(1) , 1866. doi: 10.1038/s41598-018-20251-1. Article   Pubmed

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