Excerpts

The development of mScarlet3-H marks a noteworthy advance in fluorescent protein technology. By addressing long-standing challenges related to thermal stability, chemical resilience and photostability in RFPs, this protein provides a powerful tool for advanced microscopy. From routine imaging to CLEM, STED, 3D-SIM and tissue clearing, it expands the capabilities for high-resolution, long-term imaging of dynamic biological processes. As researchers continue to refine and expand upon these promising new FPs, mScarlet3-H is poised to become a cornerstone of next-generation fluorescence imaging that demands high photostability, paving the way for deeper insights into the inner workings of cells and organisms.

Furthermore, mScarlet3-H provides high signal-to-noise ratios for dual-color STED imaging, making it a game-changer for visualizing dynamic cellular interactions at the nanoscale.