a.k.a. SN2
| Oligomerization | Organism | Molecular Weight | Cofactor |
|---|---|---|---|
| Monomer | Anthomedusae sp. DC-2005 | 26.6 kDa | - |
| Ex λ | Em λ | EC (M-1 cm-1) | QY | Brightness | pKa | Maturation (min) | Lifetime (ns) |
|---|---|---|---|---|---|---|---|
| 579 | 610 | 45 |
No photostability measurements available ... add one!
SuperNova2 was derived from SuperNova Red with the following mutations: M1_E2insGS/S10R
A monomeric red fluorescent protein called SuperNova has been recently developed, however, it demonstrates suboptimal characteristics in most phototoxicity-based applications. Here, we applied directed evolution to this protein and identified SuperNova2, a protein with S10R substitution that results in enhanced brightness, chromophore maturation and phototoxicity in bacterial and mammalian cell cultures.
Gorbachev et al. (2020)
(2020). International Journal of Molecular Sciences, 21(22) , 8800. doi: 10.3390/ijms21228800. Article Pubmed
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