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Comparison List

Channelrhodopsin2

a.k.a. ChR2, COP4

Channelrhodopsin2 is a photoactivatable long stokes shift fluorescent protein published in 2003, derived from Chlamydomonas reinhardtii. It has high acid sensitivity.
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Oligomerization Organism Molecular Weight Cofactor
? Chlamydomonas reinhardtii 77.2 kDa -

FPbase ID: 4RWBQ

Attributes

Ex λ Em λ EC (M-1 cm-1) QY Brightness pKa Maturation (min) Lifetime (ns)
485 1000     7.1    

Photostability

No photostability measurements available ... add one!

Channelrhodopsin2 Sequence

MDYGGALSAVGRELLFVTNPVVVNGSVLVPEDQCYCAGWIESRGTNGAQTASNVLQWLAAGFSILLLMFYAYQTWKSTCGWEEIYVCAIEMVKVILEFFFEFKNPSMLYLATGHRVQWLRYAEWLLTCPVILIHLSNLTGLSNDYSRRTMGLLVSDIGTIVWGATSAMATGYVKVIFFCLGLCYGANTFFHAAKAYIEGYHTVPKGRCRQVVTGMAWLFFVSWGMFPILFILGPEGFGVLSVYGSTVGHTIIDLMSKNCWGLLGHYLRVLIHEHILIHGDIRKTTKLNIGGTEIEVETLVEDEAEAGAVNKGTGKYASRESFLVMRDKMKEKGIDVRASLDNSKEVEQEQAARAAMMMMNGNGMGMGMGMNGMNGMGGMNGMAGGAKPGLELTPQLQPGRVILAVPDISMVDFFREQFAQLSVTYELVPALGADNTLALVTQAQNLGGVDFVLIHPEFLRDRSSTSILSRLRGAGQRVAAFGWAQLGPMRDLIESANLDGWLEGPSFGQGILPAHIVALVAKMQQMRKMQQMQQIGMMTGGMNGMGGGMGGGMNGMGGGNGMNNMGNGMGGGMGNGMGGNGMNGMGGGNGMNNMGGNGMAGNGMGGGMGGNGMGGSMNGMSSGVVANVTPSAAGGMGGMMNGGMAAPQSPGMNGGRLGTNPLFNAAPSPLSSQLGAEAGMGSMGGMGGMSGMGGMGGMGGMGGAGAATTQAAGGNAEAEMLQNLMNEINRLKRELGE
GenBank: 5727376
UniProtKB: Q8RUT8

Structure

Deposited: ,
Chromophore:

Excerpts

No excerpts have been added for Channelrhodopsin2
Excerpts are snippets from publications that capture key information about this protein that does not easily fit into one of the existing fields (such as a summary, motivation, or observation).

Primary Reference

Channelrhodopsin-2, a directly light-gated cation-selective membrane channel

Nagel G, Szellas T, Huhn W, Kateriya S, Adeishvili N, Berthold P, Ollig D, Hegemann P, Bamberg E

(2003). Proceedings of the National Academy of Sciences, 100(24) , 13940-13945. doi: 10.1073/pnas.1936192100. Article   Pubmed

Additional References

  1. Characterization of Engineered Channelrhodopsin Variants with Improved Properties and Kinetics

    Lin Jy, Lin Mz, Steinbach P, Tsien Ry

    (2009). Biophysical Journal, 96(5) , 1803-1814. doi: 10.1016/j.bpj.2008.11.034. Article   Pubmed

External Resources

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